Posts Tagged ‘Drugs’
Oral Lipid-Based Formulations: Enhancing the Bioavailability of Poorly Water-Soluble Drugs (Drugs and the Pharmaceutical Sciences) Reviews
Oral Lipid-Based Formulations: Enhancing the Bioavailability of Poorly Water-Soluble Drugs (Drugs and the Pharmaceutical Sciences)Oral lipid-based formulations are attracting considerable attention due to their capacity to facilitate gastrointestinal absorption and reduce or eliminate the effect of food on the absorption of poorly water-soluble, lipophilic drugs. Despite the obvious and demonstrated utility of these formulations for addressing a persistent and growing problem of major significance, the pharmaceutical industry has been slow to apply and further develop this technology. This title provides a comprehensive summary of the theoretical and practical aspects of oral lipid-based formulations for use in industry, and provides further insights into a developing technology expected to assume increasing prominence in years to come.
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This book describes, with references to key source materials, the background to, and conduct of, the principal nonclinical studies that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its role in the development of pharmaceuticals, the book proceeds to detail international regulations (including the impact of the new REACH standards for chemical safety), interdisciplinary interactions among scientists in drug development, steps in toxicity testing, and risk management. Further, the book covers the methods of genetic toxicology (assays, genomics, in vivo screening) as a complement to “traditional” toxicology in the risk assessment and risk management of pharmaceuticals.
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Many people have expressed a curiosity concerning how do pharmaceutical drugs get in drinking water?
I don’t think that anyone was truly surprised when an investigative team announces something like, “probe finds drugs in drinking water.”
This kind of newly discovered chemical contamination has been a problem for many years now.
So, how do pharmaceutical drugs get in drinking water?
It’s an interesting question with a somewhat startling answer.
Some of the contamination comes from the human excretion of unused portion of prescription drugs in our systems, but that is only a miniscule introduction to the water supply.
The major reason why we find ourselves in a situation where a probe finds drugs in drinking water falls directly on the pharmaceutical companies themselves.
It is due to the fact that the recommendation that they given to both the medical profession and to the public is that the best method of disposing of outdated or unused drugs is to simply flush them down the toilet.
That was what I meant when I said that the answer to how do pharmaceutical drugs get in drinking water was startling.
To have the audacity to suggest that the drugs be “safely” disposed of in this manner is just another sign of the lack of forethought on the part of the pharmaceutical industry and other large companies.
They had to know that that the end results would not be good.
When a probe finds drugs in drinking water, fingers need to be pointed at both the pharmaceutical companies AND the medical professionals, both of whom acted irresponsibly.
They had to realize that they were further contaminating an already impure drinking water supply, but nobody seems to want to take responsibility for their actions.
Okay, so now that we have answered the question as to how do pharmaceutical drugs get in drinking water, what are we going to do about it?
According to the U.S. Environmental Protection Agency and the water authority representatives, we should carry on with our lives without concern.
Neither agency seems to think that we have anything to worry about.
Any time though that a probe finds drugs in drinking water we have something to be concerned about.
The same goes for any new contaminant that may be found.
All of these chemical toxins feed off of each other and become infinitely stronger, despite the fact that they are individually found in only trace amounts.
We shouldn’t even have to be asking questions such as how do pharmaceutical drugs get in drinking water, because they shouldn’t be in the water supply in the first place.
There are simple technologies that are available for use in the privacy of our own homes that can prevent this kind of contamination, but the EPA ant the water authorities refuse to use this technology on a large scale.
That a probe finds drugs in drinking water is not a laughing matter.
We must protect our own health through the purchase of a home drinking water purification system today, since the powers that be have no inclination to do it.
How do pharmaceutical drugs get in drinking water?
The drugs get there through incompetence and irresponsibility, that’s how.
Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form, Second Edition (Drugs and the Pharmaceutical Sciences)
Pharmaceutical Preformulation and Formulation: A Practical Guide from Candidate Drug Selection to Commercial Dosage Form (Drugs and the Pharmaceutical Sciences)
This timely Second Edition reflects the mounting pressure on pharmaceutical companies to accelerate the new drug development and launch process, and the shift from developing small molecules to the growth of biopharmaceuticals. It meets the need for up-to-date and advanced information for drug preformulation and formulation, and addresses the current trends in the continually evolving pharmaceutical industry.
Ideal for practitioners working in the pharmaceutical industry (including R&D scientists, technicians, and managers), as well as undergraduate and postgraduate courses in industrial pharmacy and pharmaceutical technology, this text addresses:
How To Lose Weight Overnight All Natural Dietary Supplements And Natural Weight Loss
Are you one of those people who constantly try the latest weight loss fad only to end up in an unfortunate yo-yo diet? You might be surprised just the reasons why you are yo-yoing. Here you will find out about the shocking discoveries on the best weight loss pills on the market and just what might be a better option for you.
Loosing weight does not get any easier than this. Are you tired of all the weight loss options that just don’t work.
Loosing weight does not have to be hard and can be easy if you do some reading.
Easy Weight Loss Tea also known as the Wu-Yi tea which is grown on the WuYi mountains in China. This is a type of Oolong Tea that has been used by the Chinese for centuries as medicine and has been proven to cause weight loss.
In affiliate marketing choosing the right niche is as important as anything else and both fitness and weight loss are popular topics – both off – and online. The popularity of niches such as these presents the affiliate marketer with both problems and possibilities; for the right person this could be a virtual goldmine.
Obesity is a growing concern for many people. This is why a lot of people try to find the most effective and fast weight loss methods to avoid the health risks that go with this condition. However fast weight loss does not necessarily mean that you will lose weight overnight. This process happens gradually. But if you consider fast weight loss as losing about � to 1 pound a week then you can rely on three effective strategies to achieve this.
Once you have completed your hCG weight loss protocol how do you reintroduce the foods again without regaining the weight? You have just spent weeks on the VLCD (Very Low Calorie Diet) and now how do you eat again and not gain weight.
They say no single food can make us lose weight and so it means a single food group is not enough to help us with our weight reduction program. We know that our bodies do not actually burn all the calories we have so some of these unused calories become bad cholesterol and also turn into body fats.
Weight loss programs can be broadly categorized as clinical and non-clinical. Understanding the nature of each of these programs will help you a lot in finding a program that suits your requirements. A clinical weight loss program includes the service provided by health care assistants and hospitals that give guidance to the individuals who wish to reduce their body weight for various reasons. A clinical program involves one or more qualified doctors dietitians nursing assistants and psychologists. It need not always be a commercially owned one like a non-clinical weight loss program run by private parties.
An investment in the best kitchen water filter that money can buy is a sound investment in the future health of your family. You may not realize it, but the contaminants present in our reservoir systems have a tremendous impact on the health of everyone in the United States, and worldwide. What we have done to our water supply is a serious matter, and one day it will come back to affect you.
None of us are safe from the tens of thousands of industrial chemicals and pharmaceuticals currently present in our water supply. We tend to think that because we live in one of the most highly technological nations in the world, that we are somehow immune from the effects of pollutants in our water supply. Our superior technology, however, does not trickle down to the facilities that treat our water.
The reason that you need to seek out the best kitchen water filter you can possibly find is that your municipal water treatment facility does not have the ability to remove even a single chemical agent from your drinking water! The equipment they use is typically only capable of sand bed filtration, and is really not much different than a huge swimming pool filter. These facilities haven’t changed much at all over the last 100 years.
Originally, the sole purpose of water filtration was to remove particulates from the water, and to disinfect to cut down on the occurrence of waterborne diseases. This is basically the same level of service that you are getting now. The porous membrane filters that “clean” your water cannot remove substances of equal or lesser molecular weight than water, so every chemical agent present slips right through.
To emphasize how much of an impact the contaminants in our drinking water have, you should think about the fact that while many illnesses in the past could not be linked to any known cause, most are now proven to be associated with the toxins present in our drinking water.
The best kitchen water filter can remove 99% of these toxins, and will keep you and your family members from developing the illnesses linked to toxins in the water.
Don’t fool yourself into believing that following the current trend of drinking bottled water is going to protect you. Nearly none of the bottled water that is available comes from a “fresh mountain stream” as many believe. The vast majority of the bottled water you drink comes straight from a tap, and it is only filtered to improve taste and odor.
The very best kitchen water filter features a multi media block and granular activated carbon filter for ensuring that your water is free of chemical contaminants. Then a submicron filter traps the carcinogenic cysts resistant to the chlorine disinfection process, while an ion exchange removes traces of toxic metals from your water. This is the measure of protection required to keep you and your family healthy.
With the current threat to your family’s health well documented, why wouldn’t you want the best kitchen water filter in your home?
The belief associated with commerce has completely changed by going online. The Online Pharmacy got a significant increase from this adaptation and has turned into a medium for the dealings and conversation. The pharmaceutical business has totally developed and evaluated the ability of the internet.
So, what is an online pharmacy? It basically deals with the transfer or promoting of drugs over the world wide web. As it saves ample time lots of people have left the old system of buying drugs or goods. The need is principally because it’s inexpensive in the costly marketplace of medication, and not required to have prescription to support the offer. It also allows for online prescription with assistance through in-house doctors; these people recommend based on the requirements and mostly tend to be cost free. The western part of the planet usually enjoys this method of trade, North America becoming the protagonist.
The medicine is generally created in other countries where the required ingredients for most of medicines and human resource are very economical. Canadian online pharmacies are well-known for its prominence within the US as well as worldwide pharmacy marketplace.
This has been proven as very reasonable and assure full protection from any deceit. They follow the tradition made by the FDA as well as CIPA. FDA stands for Food and Drug Administration and implements set of laws associated with any food and drug product sold anywhere throughout The united states. CIPA stands for Canadian International Pharmacy Association and provides approved retail trade of medication and it permits mail-order providers.
Uncomplicated possession of any illegal thing without proper recommended program may yield detainment of up to one year along with a penalty of $ 1,000. The FDA generally recognizes “face to face” link between doctors and patients. There are some established processes that come under the FDA as well as section 301.
Just the registered Canadian pharmacies can do business. The drug ought to be imported through licensed drugstore for personal use. A legitimate prescription should accompany the bought medicines. The drug ought to be permitted by FDA and should meet the standards. FDA offers other set of guidelines with regard to infringement under section 301 however these rules are given the main concern.
The year 2005 launched everybody to a completely different type of deceitful exercise commonly known as “Canadian Pharmacies”, which was a scam process running a pharmacy business and since that time all legitimate Canadian pharmacies are afflicted by this particular hoax. Because this business is totally reliant on the web so we should check for scams before we get in any kind of transaction.
Pharmaceutical drug development is the development of gas stations – new drugs – the pharmaceutical industries
Start a new comprehensive medical reform, the industry welcome the development of a new starting point. New situation, we face four major new opportunities, that health system reform, the promotion of Medicine Rapidly expanding market; capital markets favor pharmaceutical industry; strong demand in international market drugs; industrial concentration strengths. Summarize the past 50 years business development experience, we are deeply aware, and unswervingly follow the road of independent innovation is the rapid development of enterprises, and maintain a leading position in the industry, the only “shortcut.”
Although pharmaceutical companies invested heavily in new product development, variables huge and long, but, if successful, will receive a high return, high-yield. New Drug R & D is Pharmaceutical companies Development of gas stations. No technical advantages, the market would be difficult to take advantage. As the first development and production of controlled release formulations of local enterprises, Qingdao Yellow Sea Pharmacy China has maintained sustained and controlled release technology leadership. In recent years, the profit a year from 8% to 10% for science and technology investment in experienced by the laboratory to the Institute, to the Technology Center’s “upgrade”, the company has formed a complete set of independent R & D system . In the effort to build an innovative system, we also fully recognize that, for enterprises, innovation is essential, and focus are very important. Deep in the fields of business to do so refined, not only for the people to provide more effective, higher quality products, but also stand out in the same industry, take the initiative in the market. Thus, we focus on cardiovascular drugs and endocrine system drugs These two directions, the pursuit of business specializes in surgery, is committed to sustained and controlled release technology-based new product development, restructuring 5 years, successfully developed six new products and has 13 projects in research.
Through unremitting efforts, we are happy to try and focus on innovation and R & D strategy implementation brought about fruitful results. Currently, as few can at the same time domestic production of controlled release preparations of 5 companies, our main products nifedipine, Matt United States, TRINITY Lee, Yuen Shun and other marketing nationwide. Which nifedipine antihypertensive drugs has become the leading domestic brands. We plan to invest nearly 400 million yuan to build the area of 200 acres of “medical high-tech industrial park” in a project?? R & D, production, Sell In one efficient, sustained and controlled release preparation base was opened in 2003. Currently, the Industrial Park Phase II?? Annual production capacity to reach 2.5 billion in the solid preparation is stepping up construction of technological transformation projects. We strive to further improve the business of solid controlled release technology platform, successfully developed a pulse, targeted drug delivery formulations.
R & D strength to develop even more powerful enterprise. In the future, our confidence in the consolidation of controlled release technology based on the dominant position, to develop bio-pharmaceuticals, the development of marine drugs, stronger businesses, big brands. At the same time, we also strive to be introduced by Dr. more high-end talent, work to establish postdoctoral mobile stations, the establishment of a professional, young R & D team; to controlled release technology research and development objectives, to further build osmotic pump, pulse to medicine, hour delivery technology platforms such as drug delivery systems; Industrial Park Phase III project with the Beijing Union Hospital Joint R & D institutions set up?? “Beijing Union Technology Development Co., Ltd. Yellow Sea”, to increase R & D reinforce the foundation.
Well pharmacy, for the benefit of mankind; tree of the Yellow Sea brand, a century company. Qingdao Yellow Sea is always the pursuit of innovation and development of pharmaceuticals.